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Understanding more about the catalytic mechanism used by these enzymes will be especially important for further developing drug candidates that effectively block their enzymatic activity

Yes, glutathione is widely regarded as beneficial for skin whitening due to its antioxidant and anti-melanogenic effects, which help reduce melanin production

Also, SLC7A11 is negatively modulated by activating transcription factor 3 and p53 at the transcriptional level (Koppula et al., 2021a)

Further discussion of these factors is beyond the scope of this article